Vincent Asanda Busa
Chemist/Researcher
Cape Town
Summary
A committed and adaptive chemist/researcher with over 7 years of chemical analysis and analytical method development experience at university and industrial level, respectively, that possesses a strong design, development, QC and stability tests background on pharmaceutical products. My extensive knowledge and experience on HPLC/UHPLC, LC-MS, GC-MS, cGMP and ISO is backed by years in pharmaceutical environment and vaccine design with meticulous details at following procedure, producing quality results with high accuracy, complying to international standards and meeting deadlines.
Overview
10
10
years of professional experience
10
10
years of post-secondary education
Work History
ANALYTICAL METHOD DEVELOPER
University of the Western Cape
08.2018 - 12.2023
- Created analytical experimental conditions for diverse APIs for pharmaceutical collaborators
- Evaluated and validated developed analytical methods in order to identify, separate and quantify manufacturing
- Prepare and analyze samples according to SOPs
- Prepare and operate laboratory equipment according to SOPs
- Perform calibration checks on equipment according to calibration procedure, to ensure accurate results
- Maintain good housekeeping
- Perform HPLC/GC analysis using MOA
- Check HPLC/GC runs regularly during analysis/shift.
- Employed SDLC methodologies during multiple projects, streamlining cross-discipline development
- Drove UI requirements through to implementation, complete with accurate sizing estimates and task breakdowns
- Used Agile planning principles to deliver tailored solutions that met customer requirements
Chemical Analyst
Cape Peninsula University of Technology
01.2017 - 08.2018
- Optimize and facilitate implementation of current processes
- Propose changes or improvements to processes, tools and techniques.
- Manage approval of laboratory raw data and investigation of out-of-specification results where applicable
- Performed chemical tests to assist scientists in making qualitative and quantitative analyses of solid, liquid and gaseous materials
- Operated laboratory equipment and prepared compounds and solutions to conduct tests
- Composed technical reports and charts to document experimental test results
- Developed over 20 new products and prepared reports as well as technical papers for tests, products and processes
- Tested titration of chemical tanks in production line to check for ideal pH and other chemical levels and balance ratios
- Calibrated and maintained laboratory spectrometers and chromatographs
- Created spreadsheets and other forms of documentation to accurately record and calculate analytical results
- Communicated analysis results to various departments and stakeholders to effectively formulate products
- Troubleshot equipment adjustments to meet and maintain safety, output and quality expectations
- Collaborated with supervision, engineering and other personnel on quality and performance improvements
- Performed analysis of pharmaceutical finished products using various methods to test for purity
- Developed methodologies to identify pesticide residues in pharmaceutical products
- Examined inoperative or malfunctioning production equipment to diagnose source of trouble
SENIOR RESEARCHER
Lund University (Sweden)
04.2017 - 07.2018
- Synthesized and characterized active pharmaceutical ingredients (API) using appropriate analytical techniques
- Investigated drug metabolism and pharmacokinetics
- Maintained routine lab safety, monitored GMP and GLP.
- Managed documentation according to company guidelines and compliance requirements
- Presented findings and demonstrated concepts at conferences and events
- Obtained funding and worked with backers to assess research goals and implement relevant plans
- Maintained research materials, equipment and facilities in good working order
- Collaborated with leadership team to identify relevant questions and determine best methods of collection
- Wrote research papers, reports, reviews, and summaries regarding bioorganometallic chemistry
DRUG DEVELOPER RESEARCHER IN TB
CSIR
01.2015 - 12.2015
- Investigated structure-based drug relationship
- Synthesized and characterized TB drugs
- Created appropriated AMD for drugs
- Investigated computational interaction of drugs with receptors.
- Applied theories and methods of life sciences to interpret and perform analyses of experimental results
- Followed health and safety regulations while handling dangerous or toxic substances
- Advised or assisted in obtaining patents or meeting other legal requirements
- Learned new laboratory techniques and applied expertise in carrying out enhanced experiments under supervision of senior lab members
- Performed accurate quantitative analysis of targeted data research, collection and report preparation
- Detailed study findings and updated research upon new discoveries
- Worked as member of integrated project team in highly collaborative work environment
- Reviewed technical and professional publications and journals to stay current on recent literature and make more strategic research decisions
SENIOR COLLABORATIVE RESEARCHER
UWC, Kenyatta University (Kenya), DUT and CSIR
01.2014 - 12.2014
- Responsible for AMD and AMV
- Investigated Absorption, Distribution, Metabolism, Excretion, Toxicity (ADMET).
- Performed research into study topics to increase knowledge and to provide valuable contributions
- Gathered and organized information for research purposes
- Collaborated with leadership team to identify relevant questions and determine best methods of collection
- Synthesized data and wrote detailed reports to present research findings to stakeholders
- Developed research proposals, identified research objectives and created research plans
- Analyzed and interpreted patterns and trends
- Identified sources of funding to prepare research proposals and submit funding applications
- Developed data collection strategies and monitored data quality for optimal research results
- Requested or acquired equipment or supplies necessary for projects
- Proposed innovative methods for capturing and analyzing customer data
- Sorted data into well-organized formats and transformed into figures
- Utilized statistical packages to analyze data and create visualizations
Education
Ph.D. - Medicinal And Pharmaceutical Chemistry
University of The Western Cape
Cape Town, South Africa 04.2014 - 04.2017
Ph.D. - Medicinal And Pharmaceutical Chemistry
Lund University
Lund, Sweden 04.2013 - 04.2014
Master of Science - Chemical Catalysis
University of The Western Cape
Cape Town, South Africa 02.2012 - 03.2013
Master of Science - Catalysis
Lund University
Lund, Sweden 02.2011 - 02.2012
Bachelor of Science - Chemical Sciences Honors
UWC
Cape Town, South Africa 02.2010 - 03.2011
Bachelor of Science - Chemical Sciences
University of The Western Cape
Cape Town, South Africa 02.2007 - 03.2010
Skills
Regulatory complianceundefined
References
- Prof. Fanelwa Ajayi, Associate Professor, Analytical Chemistry, University of the Western Cape, +27 (021) 959-3049, fngece@uwc.ac.za
- Dr. Masande Yalo, Lecturer, Organic/Pharmaceutical Chemistry, Cape Peninsula University of Technology, +27 (021) 959 4516, yalom@cput.ac.za
- Mr. Adrian De Villiers, Instrumentation Technician/LIMS Administrator, Aspen Pharmaceuticals, +27 72 434 2211, ADeVilliers@aspenpharma.com
Timeline
ANALYTICAL METHOD DEVELOPER
University of the Western Cape
08.2018 - 12.2023
SENIOR RESEARCHER
Lund University (Sweden)
04.2017 - 07.2018
Chemical Analyst
Cape Peninsula University of Technology
01.2017 - 08.2018
DRUG DEVELOPER RESEARCHER IN TB
CSIR
01.2015 - 12.2015
Ph.D. - Medicinal And Pharmaceutical Chemistry
University of The Western Cape
04.2014 - 04.2017
SENIOR COLLABORATIVE RESEARCHER
UWC, Kenyatta University (Kenya), DUT and CSIR
01.2014 - 12.2014
Ph.D. - Medicinal And Pharmaceutical Chemistry
Lund University
04.2013 - 04.2014
Master of Science - Chemical Catalysis
University of The Western Cape
02.2012 - 03.2013
Master of Science - Catalysis
Lund University
02.2011 - 02.2012
Bachelor of Science - Chemical Sciences Honors
UWC
02.2010 - 03.2011
Bachelor of Science - Chemical Sciences
University of The Western Cape
02.2007 - 03.2010
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