Summary
Overview
Work History
Education
Skills
References
Websites
Timeline
Generic

Sakhile Sithole

Centurion

Summary

I am a results-driven healthcare professional with a strong foundation in clinical laboratory systems, HIV diagnosis, biomarker-based population studies, and client account management. With over 15 years of experience in laboratory operations, project coordination, and stakeholder engagement across public health and clinical research settings, I bring a unique blend of technical expertise and strategic relationship management. Currently serving as Senior Laboratory Manager at Wits Health Consortium, under the Diagnostic Innovation Hub (DIH) division. I lead cross-functional teams across clinical trials, safety, PBMC processing, and biorepository operations. I have successfully collaborated with global sponsors and clinical sites, ensuring high standards of service delivery and regulatory compliance. My experience includes leading client-facing functions, contract oversight, and aligning service capabilities with client expectations—key to excelling in key account management within pharma and healthcare environments. Strategic and people-focused, with proven leadership in financial oversight, quality systems implementation, client engagement, and process optimization. Passionate about mentoring teams, and driving continuous improvement within regulated environments.

Overview

16
16
years of professional experience

Work History

Senior Laboratory Manager

Wits Health Consortium – WITS Diagnostic Innovation Hub
Johannesburg
01.2024 - Current
  • Provide strategic leadership as a member of the senior management team, contributing to WITS DIH growth and operational planning
  • Oversee clinical trials project management, laboratory and pre-laboratory functions, ensuring efficiency, compliance, and adherence to quality standards
  • Manage staffing, procurement, and stock control to optimize resources and minimize operational costs
  • Implement and monitor total quality management systems for compliance with research protocols and client agreements
  • Support pathologists in charge, oversee biorepository functions, and manage client and clinician interactions.

Laboratory Manager

04.2023 - 01.2024
  • Coordinated daily storage, labeling, and data input of clinical trial sample aliquots onto the LDMS system
  • Oversaw sample retrieval, shipment logistics, and compliance with storage and safety protocols
  • Ensured calibration and maintenance of biorepository equipment for regulatory compliance
  • Managed a team of LDMS coordinators, providing training and mentorship to uphold high-quality standards.

Regional Laboratory Advisor

ICAP South Africa
Pretoria
10.2017 - 03.2023
  • Provided technical support to multiple African countries implementing the PEPFAR-funded PHIA survey
  • Developed and implemented SOPs for laboratory assessments, biomarker testing, and sample management
  • Conducted biomarker training and project management support in Lesotho, Kenya, Rwanda, Tanzania, Eswatini, Mozambique, and Haiti
  • Led laboratory quality improvement initiatives, ensuring adherence to HIV rapid testing, viral load, and PCR assays
  • Provided technical guidance on material transfer agreements and import permits for specialized testing.

Project Laboratory Advisor

ICAP Lesotho
03.2017 - 03.2023
  • Trained over 220 PHIA staff in biomarker-related activities, including HIV rapid testing, CD4 PIMA POC, and plasma separation
  • Ensured laboratory specimen data accuracy and collaborated with data teams to clean and validate records
  • Monitored and reviewed weekly quality assurance reports and implemented corrective actions
  • Led laboratory recruitment, managing a team of 22 technologists and providing ongoing mentorship.

District Laboratory Coordinator

Beyond Zero, IYDSA
Ixopo
05.2013 - 03.2016
  • Developed and adapted SOPs for specimen collection, storage, and transportation
  • Conducted laboratory assessments and training in pre-analytic, analytic, and post-analytic quality control
  • Implemented laboratory-clinical interface improvements, strengthening relations between National Laboratory Services and Department of Health facilities.

Biomedical Technologist

National Health Laboratory Service, Inkosi Albert Luthuli Hospital
Durban
07.2009 - 02.2013
  • Performed routine diagnostic procedures in molecular testing, serology, and cell culture
  • Conducted instrument validation, troubleshooting, and maintenance to ensure consistent test performance
  • Assisted in research projects on flu surveillance and CMV prevalence
  • Developed and reviewed SOPs, training materials, and quality assurance documentation.

Education

Bachelor of Science - Biomedical Sciences – Articulation

Cape Peninsula University of Technology

B. Tech - Business Management Studies

Durban University of Technology

Diploma - Biomedical Technology

Durban University of Technology

Skills

  • SKILLS & COMPETENCIES
  • Good Clinical Laboratory Practice (GCLP) Compliance
  • Laboratory Operations & Quality Management
  • Clinical Trials Project Management
  • Molecular Diagnostics & Virology Testing
  • Biomarker Training & Capacity Building
  • Clinical Trial Sample Management
  • SOP Development & Implementation
  • Strategic Planning & Team Leadership
  • Laboratory Data Management & Analysis
  • Regulatory Compliance & Risk Mitigation
  • CERTIFICATIONS & TRAINING
  • Good Clinical Laboratory Practice (GCLP)
  • Health and Safety Officer Training
  • Project Management for Health Professionals
  • Laboratory Quality Management Systems

References

References Prof. Jaya George Director Laboratory Services Jaya.george@wits.ac.za +27 82 325 7493 Blessing Kadira Strategic Development Manager WITS DIH Blessing.kadira@witsdih.ac.za +27 71 292 5271 Dr Herbert Longwe Global Deputy Director, Laboratories Columbia University (ICAP) hl2954@cumc.columbia.edu +27 76 512 1077/ +27 74 738 6012 Clarise Shezi District Manager (2016) Beyond Zero claricemthembu@gmail.com +27 82 690 1379/ +27 83 783 7957

Timeline

Senior Laboratory Manager

Wits Health Consortium – WITS Diagnostic Innovation Hub
01.2024 - Current

Laboratory Manager

04.2023 - 01.2024

Regional Laboratory Advisor

ICAP South Africa
10.2017 - 03.2023

Project Laboratory Advisor

ICAP Lesotho
03.2017 - 03.2023

District Laboratory Coordinator

Beyond Zero, IYDSA
05.2013 - 03.2016

Biomedical Technologist

National Health Laboratory Service, Inkosi Albert Luthuli Hospital
07.2009 - 02.2013

Bachelor of Science - Biomedical Sciences – Articulation

Cape Peninsula University of Technology

B. Tech - Business Management Studies

Durban University of Technology

Diploma - Biomedical Technology

Durban University of Technology
Sakhile Sithole