Accomplished Medical Research Scientist with a PhD in Medical Microbiology and 10 years of experience in scientific research. Currently serving as Clinical Lead at IQVIA, adept at managing large-scale, multi-country clinical trials from inception to execution. Demonstrates expertise in study operations optimization, regulatory compliance, and risk management, with a proven track record in site selection and patient recruitment. Recognized for strong stakeholder engagement and strategic problem-solving abilities, complemented by extensive scientific writing experience and numerous first-author publications.
1. Perumal R, Khan A, Naidoo K, Ngema SL, Nandlal L, Padayatchi N, Dookie N. Mycobacterium tuberculosis Intra-Host Evolution Among Drug-Resistant Tuberculosis Patients Failing Treatment.Infect Drug Resist. 2023 May 9:16:2849-2859. doi: 10.2147/IDR.S408976. eCollection 2023.
2. Ngema SL, Dookie N, Permumal R, et al. Isoniazid resistance-conferring mutations are associated with highly variable phenotypic resistance. J Clin Tuberc Other Mycobact Dis.2023.
3. Naidoo K & Dookie N, Can the GeneXpert MTB/XDR deliver on its promise of Expanded, Near-Patient TB Drug-Susceptibility Testing? 2021, Lancet Inf Dis, 2022.
4. Tuberculosis Elimination in the Era of COVID-19: A Moving Target, Dookie N, Padayatchi N & Naidoo K, 2020, Clinical Infectious Diseases
5. Individualised treatment of Multi-Drug Resistant Tuberculosis using whole genome sequencing and expanded drug susceptibility testing, Dookie N, Padayatchi N, Lesseks RJ, Naicker CL, Chotoo S & Naidoo K, 2020, Clinical Infectious Diseases
6. Resistance profile of Neisseria gonorrhoeae in KwaZulu-Natal, South Africa questioning the effect of the currently advocated dual therapy, Rambaran S, Naidoo K, Dookie N, Moodley P & Sturm AW, 2019, Journal of Sexually Transmitted Diseases
7. Recurrent tuberculosis among HIV co-infected patients: A Case Series from KwaZulu-Natal, Naidoo K, Dookie N, Naidoo K, Bhushan A, Govender D, Gengiah S & Padayatchi N, 2018, Journal of Infection & Drug Resistance
8. Insights into Recurrent Tuberculosis: Relapse Versus Reinfection and Related Risk Factors, Naidoo K & Dookie N, 2018, In-Tech Open
9. Evolution of Drug Resistance in Mycobacterium tuberculosis: A Review on the Molecular Determinants of Resistance and Implications for Personalised Care., Dookie N, Rambaran S, Padayatchi N, Mahomed S & Naidoo K, 2018, Journal of Antimicrobial Chemotherapy
10. Whole genome sequencing for the management of drug-resistant TB in low income high TB burden settings: Challenges and implications, Mahomed S, Naidoo K, Dookie N & Padayatchi N, 2017, Journal of Tuberculosis
11. Mechanisms of first-line antimicrobial resistance in multi-drug and extensively drug resistant strains of Mycobacterium tuberculosis in KwaZulu-Natal, South Africa, Dookie N, Sturm AW & Moodley P, 2016, BMC Infectious Diseases
12. Moxifloxacin resistance in the F15/LAM4/KZN extensively drug-resistant strain of Mycobacterium tuberculosis, Dookie N, Sturm AW & Moodley P, 2014, Journal of Infection & Drug Resistance