Boitumelo Petsoane
Production Technologist
Pretoria
Summary
Production Technologist equipped with extensive experience in the Veterinary Pharmaceuticals Industry. Adept in cell culture, viral & bacterial antigen manufacturing, quality control and vaccine formulations. Very eager further diversify my knowledge and skills within the biological sphere.
Overview
5
5
years of professional experience
5
5
years of post-secondary education
Work History
Production Technologist
ONDERSTEPOORT BIOLOGICAL PRODUCTS
Pretoria
06.2020 - Current
- Responsible for propagation and maintenance of high quality working cell lines: BHK, CFK, MDBK and Vero cells in accordance with SOP’s and regulatory requirements
- Managing technical assistants performance and ensure training, competency, and skills development plans are in place.
- Reviewed SOPs, batch documents, operational risks and participate in quality assurance audits.
- Configured production structures on Navison Enterprise Resources Planning platform and ensured adequate stock management.
- Collaborating with operations departments involved in upstream and downstream processing of raw materials and/or vaccine products to compile and implement monthly production schedules and streamline process
- Improved production efficiency by maintaining 95% production success rate and yield outputs.
- Conduct research and implementation of improved production technologies as part of continuous improvement.
- Conduct quality control & performance testing of intermediate raw material and consumables utilized during production.
- Process control management; ensured database are updated and results trending reported monthly
- Troubleshooting and analysis of product failure incidents; efficient submission and completion of NCR reports and CAPA actions.
- Timeous procurement of consumables and new Equipment as per Capex plan; ensuring equipment service/validation and maintenance.
- Adhered to SHEQ Compliance in terms of the OHS ACT, ensuring compilation and submission of reports Accidents/incidents, equipment management, environmental impact for operations
Manufacturing Technologist
DELTAMUNE PTY
08.2019 - 02.2020
- Manufacturing and bottling of vaccines, biological products, and subcontracted product as per standard operating procedures and in compliance with cGMP and ISO 9000 requirements
- Efficient preparation, completion, and review of production batch records
- Maintenance and servicing of formulation plants and supporting equipment in compliance with legal and safety requirements
- Planning, design, construction and commissioning of new equipment and processes as required by QA department
- Assist in implementation of quality systems in various departments within scope of operation
- Follow TQMS requirements and timeously perform investigations as needed
- Manage team tasks and ensure continued efficient productivity ; ensure that team receives training on SOP’s and that training files are maintained
- Compile skills development plan for staff and scheduling relevant training and provide training where needed.
Production Technologist
DELTAMUNE PTY
02.2017 - 07.2019
- Plan, perform, and co-ordinate services rendered to various departments to ensure continuity within the production line by providing services to fermentation, quality control, freeze dried products, and final vaccine manufacturing
- Maintain service systems and ensure logbooks are completed i.e
- Boiler, pure steam, R.O water plant, air compressor, generator, fridges, incubators, etc
- Ensure that preparation, completion, and review of production batch records and data sheets is achieved timeously
- Conduct various sampling for QC purposes i.e
- Environmental monitoring, raw materials, final products, and water
- Performing sterility and viability tests for bacterial antigen
- Sterility determination of liquid raw materials and final products
- Potency and moisture determination of lyophilized viral stocks; Determination of formaldehyde percentage and viscosity of manufactured vaccines
- Up-stream processing of bacterial culture for production of antigen
- Fermentation and operation of bioreactors and pressure vessels for in-situ sterilization
- Cultivation of viruses in chicken embryo for production of antigen
- Inoculations via CAM, AS and IV routes.
Education
National Diploma - Biotechnology
Tshwane University of Technology
Pretoria, GP 01.2012 - 01.2017
Skills
Root Cause analysisundefined
Timeline
Production Technologist
ONDERSTEPOORT BIOLOGICAL PRODUCTS
06.2020 - Current
Manufacturing Technologist
DELTAMUNE PTY
08.2019 - 02.2020
Production Technologist
DELTAMUNE PTY
02.2017 - 07.2019
National Diploma - Biotechnology
Tshwane University of Technology
01.2012 - 01.2017
Similar Profiles
Ramasela Charlotte MontjaRamasela Charlotte Montja
Administration Officer at ONDERSTEPOORT VETERINARY ACADEMIC HOSPITALAdministration Officer at ONDERSTEPOORT VETERINARY ACADEMIC HOSPITAL
Jirapa ( Fern ) WongkitikhunakonJirapa ( Fern ) Wongkitikhunakon
Production Operators at Biological TherapiesProduction Operators at Biological Therapies
Kranthi Kumar PottolaKranthi Kumar Pottola
HR Business Partner - Sr. Associate at Biological E. LimitedHR Business Partner - Sr. Associate at Biological E. Limited
Wernich BotesWernich Botes
Financial Accountant at Feenstra Group Property Developers and ManagersFinancial Accountant at Feenstra Group Property Developers and Managers
Murangi NetshisauluMurangi Netshisaulu
Intern: Financial Management Grant at City Of Tshwane MunicipalityIntern: Financial Management Grant at City Of Tshwane Municipality