
To seek and maintain full-time position that offers professional challenges utilizing interpersonal skills, excellent time management and problem-solving skills. Detail-oriented team player with strong organizational skills. Ability to handle multiple projects simultaneously with a high degree of accuracy.
Publications (Research Output)
Malose J Mphahlele, Eugene E Onwu, Emmanuel N Agbo, Marole M Maluleke, Garland K Moore, Yew Siew Choong,; Synthesis In Vitro and in Silico enzyme (COX-1/2 & LOX-5), free radical scavenging and cytotoxicity profiling of the 2,4-dicarbo substituted quinazoline 3-oxides Medicinal Chemistry Research, 2022, 10, 146-164
Malose J Mphahlele, Emmanuel N Agbo, Kgosi, G Moore, Samantha Gildenhuys; In Vitro Enzymatic and Kinetic Studies, and In Silico Drug-Receptor Interactions, and Drug-Like Profiling of the 5-Styrylbenzamide Derivatives as Potential Cholinesterase and β-Secretase Inhibitors with Antioxidant Properties Antioxidants, 2021, 10(5) DOI:103390/antiox10050647
Malose J Mphahlele, Emmanuel N Agbo, Choong, Y S Synthesis, Structure, Carbohydrate Enzyme Inhibition, Antioxidant Activity, In Silico Drug-Receptor Interactions and Drug-Like Profiling of the 5-Styryl-2-Aminochalcone Hybrids Molecules, 2021, 26(9), DOI:103390/molecules26092692
Emmanuel N Agbo, Samantha Gildenhuys Choong, Y S; Malose J Mphahlele, Kgosi, G Synthesis of furocoumarin–stilbene hybrids as potential multifunctional drugs against multiple biochemical targets associated with Alzheimer’s disease Bioorg Chem 2020, 101, 103997
Malose J Mphahlele, Emmanuel N Agbo, Samantha Gildenhuys and Itumeleng B Setshedi Exploring Biological Activity of 4-Oxo-4H-furo[2,3-h]chromene Derivatives as Potential Multi-Target-Directed Ligands Inhibiting Cholinesterase, β-Secretase, Cyclooxygenase-2, and Lipoxygenase-5/15 Biomolecules 2019, 9(11), 736
Malose J Mphahlele, Samantha Gildenhuys and Emmanuel N Agbo In vitro Evaluation and Docking Studies of 5-oxo-5H-furo[3,2-g]chromene-6-carbaldehyde Derivatives as Potential Anti-Alzheimer’s Agents Int J Mol Sci 2019, 20, 5451
Emmanuel N Agbo, Samantha Gildenhuys, and Malose J Mphahlele Inhibitory effects of novel 7-substituted 6-iodo-3-O-flavonol glycosides against cholinesterase and β-secretase activities, and evaluation for potential anti-oxidant properties Molecules, 2019, 24, 3500
Malose J Mphahlele, Emmanuel N Agbo and Samantha Gildenhuys Synthesis and Evaluation of the 4-Substituted 2-Hydroxy-5-Iodochalcones and Their 7-Substituted 6-Iodoflavonol Derivatives for Inhibitory Effect on Cholinesterases and β-Secretase Int J Mol Sci 2018, 19, 4112
Emmanuel N Agbo, TJ Makhafola, YS Choong, Malose J Mphahlele, P Ramasami, Synthesis, Biological Evaluation and Molecular Docking Studies of 6-Aryl-2-Styrylquinazolin-4(3H)-Ones, Molecules 2016, 21, 28
COMPUTER Computer Knowledge
Computer Fundamentals, Internet Applications, Windows XP, Microsoft Office Word, Microsoft Office Excel, Microsoft Office PowerPoint
REFERENCES:
Winston Nxumalo, PhD.
Department of Chemistry
University of Limpopo
Cell. Number: +27 (0) 825404519
Email: Winston.nxumalo@ul.ac.za
Samantha Gildenhuys, PhD.
Department of Life and Consumer Sciences
University of South Africa
Science campus, Florida Park, Rooderpoort
Cell. Number: +27 (0) 826641804
Email: gildes@unisa.ac.za
Mmonwa M M, PhD.
Department of Chemistry
University of Cape Town
Cell. Number: +27 (0) 728635795
Email: mmakwena.mmonwa@uct.ac.za
Cell. Number: +27 (0) 728635795
Email: mmakwena.mmonwa@uct.ac.za